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Our progress towards a functional HIV cure.

This Countdown outlines the critical milestones we’ve reached so far.

We still have a few more to go. Follow along with us as we pursue a functional cure for HIV.

Pending

0. Biologics License Agreement (BLA)

Given that participants in the study are living with HIV and have been given a therapeutic dose of the experimental drug, American Gene may actually see some patients go into durable remission and be able to go off of their ARTs.

Pending

1. Phase 2 Completed

Given that participants in the study are living with HIV and have been given a therapeutic dose of the experimental drug, American Gene may actually see some patients go into durable remission and be able to go off of their ARTs.

Pending

2. Phase 2 Approved

Given that participants in the study are living with HIV and have been given a therapeutic dose of the experimental drug, American Gene may actually see some patients go into durable remission and be able to go off of their ARTs.

Pending

3. First Human Efficacy

Given that participants in the study are living with HIV and have been given a therapeutic dose of the experimental drug, American Gene may actually see some patients go into durable remission and be able to go off of their ARTs.

In Progress

4. First Five Patients Show Critical Efficacy Markers

The AGT103-T gene and cell therapy was tested on participants, giving us a sneak peek at efficacy data that normally occurs in Phase 2. The initial data showed blood markers of efficacy in all five clinical trial participants.

Completed

5. DSMB Accelerates Trial

After no serious adverse events were recorded from the first 3 patients, the DSMB voted unanimously to continue the program at a faster pace. The 4th and 5th patient were treated in November 2021.

Completed

7. First Product Passes Release Testing

After Phase 1 began and the trial participants were enrolled, American Gene manufactured AGT103-T and passed an extensive panel of safety testing.

Completed

9. Phase 1 Begins

American Gene™ Phase 1 trial officially opened and started seeking trial participants.

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